MAP3K8 FISH Probe
Our MAP3K8 probe is designed to detect MAP3K8 amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP3K8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP3K8-20-RE | 20 (40 μL) | 200 μL |
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| MAP3K8-20-AQ | 20 (40 μL) | 200 μL |
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| MAP3K8-20-GR | 20 (40 μL) | 200 μL |
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| MAP3K8-20-GO | 20 (40 μL) | 200 μL |
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Gene Summary
This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
Gene Details
Gene Symbol: MAP3K8
Gene Name: Mitogen-activated Protein Kinase Kinase Kinase 8
Chromosome: CHR10: 30722949-30750762
Locus: 10p11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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