CYP1A1 FISH Probe
Our CYP1A1 probe is designed to detect CYP1A1 amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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CYP1A1-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
CYP1A1-20-RE | 20 (40 μL) | 200 μL | ||
CYP1A1-20-AQ | 20 (40 μL) | 200 μL | ||
CYP1A1-20-GR | 20 (40 μL) | 200 μL | ||
CYP1A1-20-GO | 20 (40 μL) | 200 μL |
Gene Summary
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: CYP1A1
Gene Name: Cytochrome P450 Family 1 Subfamily A Member 1
Chromosome: CHR15: 75011882-75017877
Locus: 15q24.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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