CTNNB1 FISH Probe
Empire Genomics' CTNNB1 probe is designed to detect CTNNB1 amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CTNNB1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| CTNNB1-20-BIO | 20 (40 μL) | 200 μL |
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| CTNNB1-20-DNP | 20 (40 μL) | 200 μL | ||
| CTNNB1-20-RE | 20 (40 μL) | 200 μL |
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| CTNNB1-20-AQ | 20 (40 μL) | 200 μL |
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| CTNNB1-20-DIG | 20 (40 μL) | 200 μL |
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| CTNNB1-20-GR | 20 (40 μL) | 200 μL |
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| CTNNB1-20-GO | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
Gene Details
Gene Symbol: CTNNB1
Gene Name: Catenin Beta 1
Chromosome: CHR3: 41240941-41281939
Locus: 3p22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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