HRAS FISH Probe
Our HRAS FISH probe is designed to detect HRAS amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HRAS-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| HRAS-20-RE | 20 (40 μL) | 200 μL |
|
|
| HRAS-20-AQ | 20 (40 μL) | 200 μL |
|
|
| HRAS-20-GR | 20 (40 μL) | 200 μL |
|
|
| HRAS-20-GO | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, cognitive disability, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: HRAS
Gene Name: HRas Proto-oncogene, GTPase
Chromosome: CHR11: 532241-535550
Locus: 11p15.5
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|