HLA-A FISH Probe
Our HLA-A probe is designed to detect HLA-A amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HLA-A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| HLA-A-20-RE | 20 (40 μL) | 200 μL |
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| HLA-A-20-AQ | 20 (40 μL) | 200 μL |
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| HLA-A-20-GR | 20 (40 μL) | 200 μL |
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| HLA-A-20-GO | 20 (40 μL) | 200 μL |
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Gene Summary
HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: HLA-DOB
Gene Name: Major Histocompatibility Complex, Class II, DO Beta
Chromosome: CHR6_ssto_hap7: 4211472-4215758
Locus: 6p21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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