MLLT10 FISH Probe
Our MLLT10 probe is designed to detect MLLT10 amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
Turnaround Time: 7-10 Business Days Shipping Time: 1-2 Day Expedited Shipping
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MLLT10-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| MLLT10-20-RE | 20 (40 μL) | 200 μL |
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| MLLT10-20-AQ | 20 (40 μL) | 200 μL |
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| MLLT10-20-GR | 20 (40 μL) | 200 μL |
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| MLLT10-20-GO | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
Gene Details
Gene Symbol: MLLT10
Gene Name: MLLT10, Histone Lysine Methyltransferase DOT1L Cofactor
Chromosome: CHR10: 21823100-22032559
Locus: 10p12.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Mediastinal Myeloid Sarcoma with TP53 Mutation Preceding Acute Myeloid Leukemia with a PICALM-MLLT10 Fusion Gene
This study investigated a case of myeloid sarcoma (MS), a rare tumor often misdiagnosed as malignant lymphoma, that developed into acute myeloid leukemia (AML). Along with pathologic, morphologic, and immunophenotypic characterization, FISH was used to screen for cytogenetic abnormalities. Our MLLT10 helped detect a rare PICALM-MLLT10 fusion in the patient, an abnormality consistent with disease progression to AML.