CFTR FISH Probe
Empire Genomics has developed a CFTR FISH Probe which can be used to detect CFTR gene aneusomy. The probe comes labeled in orange, and you may also choose to customize the probe to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CFTR-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| CFTR-20-GO | 20 (40 μL) | 200 μL |
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| CFTR-20-GR | 20 (40 μL) | 200 μL |
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| CFTR-20-AQ | 20 (40 μL) | 200 μL |
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| CFTR-20-RE | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: CFTR
Gene Name: Cystic Fibrosis Transmembrane Conductance Regulator
Chromosome: CHR7: 117120016-117308718
Locus: 7q31.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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