TLK2 FISH Probe
Kinase target, TLK2, located on 17q23.2, is frequently amplified in chromosome 17 and is found in ~10.5% of ER+ breast tumors. This amplification correlates with poor clinical outcome for breast cancer patients and an even worse outcome for those with ER+ breast cancer.
Empire Genomics has developed a TLK2 FISH Probe which can be used to detect TLK2 gene aneusomy. The probe comes labeled in orange, and you may also choose to customize the probe to meet your needs.
Our TLK2 FISH Probe was used in publication, Comprehensive functional analysis of the tousled-like kinase 2 frequently amplified in aggressive luminal breast cancers.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TLK2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| TLK2-20-GO | 20 (40 μL) | 200 μL |
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| TLK2-20-GR | 20 (40 μL) | 200 μL |
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| TLK2-20-AQ | 20 (40 μL) | 200 μL |
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| TLK2-20-RE | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Details
Gene Symbol: TLK2
Gene Name: Tousled Like Kinase 2
Chromosome: CHR17: 60556385-60692841
Locus: 17q23.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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