COL1A1/PDGFB Fusion Probe
Our COL1A1/PDGFB Fusion Probe is designed to detect fusions between COL1A1 and PDGFB. The probe comes labeled in green, red, and gold, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COL1A1-PDGFB-20-GRREGO (Standard Design) | 20 (40 μL) | 200 μL |
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| COL1A1-PDGFB-20-GRREAQ | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
Gene Details
Gene Symbol: COL1A1
Gene Name: Collagen Type I Alpha 1 Chain
Chromosome: CHR17: 48261456-48279000
Locus: 17q21.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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