KRT5 FISH Probe
The KRT5 gene, located on chromosome 12q13.13, codes a type II cytokeratin proteins which are coexpressed during differentiation of simple and stratified epithelial tissues. Abberations of KRT5 is commonly observed in skin cancer, breast cancer, bladder cancer, and malignant mesothelioma.
Empire Genomics has developed a KRT5 FISH Probe assay which can be used to detect KRT5 gene aneusomy. The probe comes labeled in orange, and you may also choose to customize the probe to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
KRT5-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
KRT5-20-GO | 20 (40 μL) | 200 μL | ||
KRT5-20-GR | 20 (40 μL) | 200 μL | ||
KRT5-20-AQ | 20 (40 μL) | 200 μL | ||
KRT5-20-RE | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: KRT5
Gene Name: Keratin 5
Chromosome: CHR12: 52908358-52914243
Locus: 12q13.13
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|