PRKCI FISH Probe
Our PRKC1 Probe is designed to detect PRKC1 amplifications or deletions. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRKCI-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PRKCI-20-GO | 20 (40 μL) | 200 μL |
|
|
| PRKCI-20-GR | 20 (40 μL) | 200 μL |
|
|
| PRKCI-20-AQ | 20 (40 μL) | 200 μL |
|
|
| PRKCI-20-RE | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PRKCI
Gene Name: Protein Kinase C Iota
Chromosome: CHR3: 169940219-170023770
Locus: 3q26.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|