HGF FISH Probe
Hepatocyte growth factor (HGF), located on chromosome 7q21, regulates cell growth, cell motility, and morphogenesis by activating a c-MET signaling cascade after binding to the proto-oncogenic c-Met receptor. HGF has been implicated in a variety of cancers, including of the lungs, pancreas, thyroid, colon, and breast.
Empire Genomics has developed a HGF FISH Probe which can be used to detect HGF gene aneusomy. The probe comes labeled in orange, and you may also choose to customize the probe to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HGF-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| HGF-20-GO | 20 (40 μL) | 200 μL |
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| HGF-20-GR | 20 (40 μL) | 200 μL |
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| HGF-20-AQ | 20 (40 μL) | 200 μL |
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| HGF-20-RE | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: HGF
Gene Name: Hepatocyte Growth Factor
Chromosome: CHR7: 81331443-81399452
Locus: 7q21.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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