TERT FISH Probe
Our TERT probe is designed to detect TERT amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TERT-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| TERT-20-RE | 20 (40 μL) | 200 μL |
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| TERT-20-AQ | 20 (40 μL) | 200 μL |
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| TERT-20-GR | 20 (40 μL) | 200 μL |
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| TERT-20-GO | 20 (40 μL) | 200 μL |
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Gene Summary
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: TERT
Gene Name: Telomerase Reverse Transcriptase
Chromosome: CHR5: 1253286-1295162
Locus: 5p15.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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