VHL FISH Probe
Empire Genomics' VHL probe is designed to detect the VHL gene at chromosomal region 3p25.3. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| VHL-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| VHL-20-GO | 20 (40 μL) | 200 μL |
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| VHL-20-AQ | 20 (40 μL) | 200 μL |
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| VHL-20-GR | 20 (40 μL) | 200 μL |
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| VHL-20-RE | 20 (40 μL) | 200 μL |
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Gene Summary
Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: VHL
Gene Name: Von Hippel-Lindau Tumor Suppressor
Chromosome: CHR3: 10183318-10195354
Locus: 3p25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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