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RREB1 FISH Probe

Our RREB1 Probe is designed to detect RREB1 amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs. 

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
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SKU Test Kits Buffer Dye Color Order Now
RREB1-20-OR  (Standard Design) 20 (40 μL) 200 μL
RREB1-20-RE 20 (40 μL) 200 μL
RREB1-20-AQ 20 (40 μL) 200 μL
RREB1-20-GR 20 (40 μL) 200 μL
RREB1-20-GO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Gene Details

Gene Symbol: RREB1

Gene Name: Ras Responsive Element Binding Protein 1

Chromosome: CHR6: 7107829-7252213

Locus: 6p24.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Comparison of melanoma gene expression score with histopathology, fluorescence in situ hybridization, and SNP array for the classification of melanocytic neoplasms

Melanomas with ambiguous histology can be difficult to distinguish from benign nevi. Cytogenetic tests, therefore, have proven highly useful in differentiating melanomas from benign tumors. This study tested the efficacy of FISH at genetically characterizing 70 morphologically ambiguous melanocytic tumors. Our RREB1 probe was used to identify 6p25 amplifications in the samples. Compared to a gene expression test called myPath, FISH agreed better with histopathologic interpretations, had greater sensitivity, and correlated better with molecular diagnostics.
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