TMT FISH Probe
The TMT FISH probe is designed to hybridize to the TMT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TPSG1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TPSG1-20-RE | 20 (40 μL) | 200 μL |  |
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| TPSG1-20-GO | 20 (40 μL) | 200 μL |  |
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| TPSG1-20-GR | 20 (40 μL) | 200 μL |  |
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| TPSG1-20-AQ | 20 (40 μL) | 200 μL |  |
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| TPSG1-20-DIG | 20 (40 μL) | 200 μL |  |
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| TPSG1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: TPSG1
Gene Name: Tryptase Gamma 1
Chromosome: CHR16: 1271650-1275254
Locus: 16p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TMT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TPSG1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping