THPO FISH Probe
The THPO FISH probe is designed to hybridize to the THPO gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| THPO-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| THPO-20-RE | 20 (40 μL) | 200 μL |  |
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| THPO-20-GO | 20 (40 μL) | 200 μL |  |
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| THPO-20-GR | 20 (40 μL) | 200 μL |  |
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| THPO-20-AQ | 20 (40 μL) | 200 μL |  |
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| THPO-20-DIG | 20 (40 μL) | 200 μL |  |
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| THPO-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014]
Gene Details
Gene Symbol: THPO
Gene Name: Thrombopoietin
Chromosome: CHR3: 184089772-184095932
Locus: 3q27.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: THPO FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: THPO-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping