THP FISH Probe
The THP FISH probe is designed to hybridize to the THP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UMOD-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| UMOD-20-RE | 20 (40 μL) | 200 μL |  |
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| UMOD-20-GO | 20 (40 μL) | 200 μL |  |
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| UMOD-20-GR | 20 (40 μL) | 200 μL |  |
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| UMOD-20-AQ | 20 (40 μL) | 200 μL |  |
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| UMOD-20-DIG | 20 (40 μL) | 200 μL |  |
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| UMOD-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Details
Gene Symbol: UMOD
Gene Name: Uromodulin
Chromosome: CHR16: 20344372-20364037
Locus: 16p12.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: THP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UMOD-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping