TG FISH Probe
The TG FISH probe is designed to hybridize to the TG gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
TG-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
TG-20-RE | 20 (40 μL) | 200 μL | ||
TG-20-GO | 20 (40 μL) | 200 μL | ||
TG-20-GR | 20 (40 μL) | 200 μL | ||
TG-20-AQ | 20 (40 μL) | 200 μL | ||
TG-20-DIG | 20 (40 μL) | 200 μL | ||
TG-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
Gene Details
Gene Symbol: TG
Gene Name: Thyroglobulin
Chromosome: CHR8: 133879204-134147143
Locus: 8q24.22
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TG FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TG-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping