TCIM FISH Probe
The TCIM FISH probe is designed to hybridize to the TCIM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TCIM-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TCIM-20-RE | 20 (40 μL) | 200 μL |  |
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| TCIM-20-GO | 20 (40 μL) | 200 μL |  |
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| TCIM-20-GR | 20 (40 μL) | 200 μL |  |
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| TCIM-20-AQ | 20 (40 μL) | 200 μL |  |
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| TCIM-20-DIG | 20 (40 μL) | 200 μL |  |
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| TCIM-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011]
Gene Details
Gene Symbol: TCIM
Gene Name: Transcriptional And Immune Response Regulator
Chromosome: CHR8: 40153467-40155307
Locus: 8p11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TCIM FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TCIM-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping