TAX1BP3 FISH Probe
The TAX1BP3 FISH probe is designed to hybridize to the TAX1BP3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TAX1BP3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TAX1BP3-20-RE | 20 (40 μL) | 200 μL |  |
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| TAX1BP3-20-GO | 20 (40 μL) | 200 μL |  |
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| TAX1BP3-20-GR | 20 (40 μL) | 200 μL |  |
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| TAX1BP3-20-AQ | 20 (40 μL) | 200 μL |  |
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| TAX1BP3-20-DIG | 20 (40 μL) | 200 μL |  |
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| TAX1BP3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways; for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017]
Gene Details
Gene Symbol: TAX1BP3
Gene Name: Tax1 Binding Protein 3
Chromosome: CHR17: 3566186-3571973
Locus: 17p13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TAX1BP3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TAX1BP3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping