SVIL FISH Probe
The SVIL FISH probe is designed to hybridize to the SVIL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SVIL-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SVIL-20-RE | 20 (40 μL) | 200 μL |  |
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| SVIL-20-GO | 20 (40 μL) | 200 μL |  |
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| SVIL-20-GR | 20 (40 μL) | 200 μL |  |
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| SVIL-20-AQ | 20 (40 μL) | 200 μL |  |
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| SVIL-20-DIG | 20 (40 μL) | 200 μL |  |
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| SVIL-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Several transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Apr 2016]
Gene Details
Gene Symbol: SVIL
Gene Name: Supervillin
Chromosome: CHR10: 29746276-30024730
Locus: 10p11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SVIL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SVIL-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping