STAT5A FISH Probe
The STAT5A FISH probe is designed to hybridize to the STAT5A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| STAT5A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| STAT5A-20-RE | 20 (40 μL) | 200 μL |  |
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| STAT5A-20-GO | 20 (40 μL) | 200 μL |  |
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| STAT5A-20-GR | 20 (40 μL) | 200 μL |  |
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| STAT5A-20-AQ | 20 (40 μL) | 200 μL |  |
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| STAT5A-20-DIG | 20 (40 μL) | 200 μL |  |
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| STAT5A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
Gene Details
Gene Symbol: STAT5A
Gene Name: Signal Transducer And Activator Of Transcription 5A
Chromosome: CHR17: 40439564-40463960
Locus: 17q21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: STAT5A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: STAT5A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping