SPTBN2 FISH Probe
The SPTBN2 FISH probe is designed to hybridize to the SPTBN2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPTBN2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SPTBN2-20-RE | 20 (40 μL) | 200 μL |  |
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| SPTBN2-20-GO | 20 (40 μL) | 200 μL |  |
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| SPTBN2-20-GR | 20 (40 μL) | 200 μL |  |
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| SPTBN2-20-AQ | 20 (40 μL) | 200 μL |  |
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| SPTBN2-20-DIG | 20 (40 μL) | 200 μL |  |
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| SPTBN2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]
Gene Details
Gene Symbol: SPTBN2
Gene Name: Spectrin Beta, Non-erythrocytic 2
Chromosome: CHR11: 66452719-66488870
Locus: 11q13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SPTBN2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SPTBN2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping