SPRY2 FISH Probe
The SPRY2 FISH probe is designed to hybridize to the SPRY2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPRY2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SPRY2-20-RE | 20 (40 μL) | 200 μL |  |
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| SPRY2-20-GO | 20 (40 μL) | 200 μL |  |
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| SPRY2-20-GR | 20 (40 μL) | 200 μL |  |
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| SPRY2-20-AQ | 20 (40 μL) | 200 μL |  |
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| SPRY2-20-DIG | 20 (40 μL) | 200 μL |  |
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| SPRY2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SPRY2
Gene Name: Sprouty RTK Signaling Antagonist 2
Chromosome: CHR13: 80910111-80915086
Locus: 13q31.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SPRY2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SPRY2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping