SORD FISH Probe
The SORD FISH probe is designed to hybridize to the SORD gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SORD-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| SORD-20-RE | 20 (40 μL) | 200 μL |  |
|
| SORD-20-GO | 20 (40 μL) | 200 μL |  |
|
| SORD-20-GR | 20 (40 μL) | 200 μL |  |
|
| SORD-20-AQ | 20 (40 μL) | 200 μL |  |
|
| SORD-20-DIG | 20 (40 μL) | 200 μL |  |
|
| SORD-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]
Gene Details
Gene Symbol: SORD
Gene Name: Sorbitol Dehydrogenase
Chromosome: CHR15: 45315301-45367287
Locus: 15q21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: SORD FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SORD-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping