SKIL FISH Probe
The SKIL FISH probe is designed to hybridize to the SKIL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SKIL-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SKIL-20-RE | 20 (40 μL) | 200 μL |  |
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| SKIL-20-GO | 20 (40 μL) | 200 μL |  |
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| SKIL-20-GR | 20 (40 μL) | 200 μL |  |
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| SKIL-20-AQ | 20 (40 μL) | 200 μL |  |
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| SKIL-20-DIG | 20 (40 μL) | 200 μL |  |
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| SKIL-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Details
Gene Symbol: SKIL
Gene Name: SKI Like Proto-oncogene
Chromosome: CHR3: 170075472-170110950
Locus: 3q26.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SKIL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SKIL-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping