SKAP2 FISH Probe
The SKAP2 FISH probe is designed to hybridize to the SKAP2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
SKAP2-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
SKAP2-20-RE | 20 (40 μL) | 200 μL | ||
SKAP2-20-GO | 20 (40 μL) | 200 μL | ||
SKAP2-20-GR | 20 (40 μL) | 200 μL | ||
SKAP2-20-AQ | 20 (40 μL) | 200 μL | ||
SKAP2-20-DIG | 20 (40 μL) | 200 μL | ||
SKAP2-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
Gene Details
Gene Symbol: SKAP2
Gene Name: Src Kinase Associated Phosphoprotein 2
Chromosome: CHR7: 26706687-26904341
Locus: 7p15.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SKAP2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SKAP2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping