SIGLEC8 FISH Probe
The SIGLEC8 FISH probe is designed to hybridize to the SIGLEC8 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SIGLEC8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SIGLEC8-20-RE | 20 (40 μL) | 200 μL |  |
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| SIGLEC8-20-GO | 20 (40 μL) | 200 μL |  |
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| SIGLEC8-20-GR | 20 (40 μL) | 200 μL |  |
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| SIGLEC8-20-AQ | 20 (40 μL) | 200 μL |  |
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| SIGLEC8-20-DIG | 20 (40 μL) | 200 μL |  |
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| SIGLEC8-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010]
Gene Details
Gene Symbol: SIGLEC8
Gene Name: Sialic Acid Binding Ig Like Lectin 8
Chromosome: CHR19: 51954250-51961708
Locus: 19q13.41
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SIGLEC8 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SIGLEC8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping