SH3BP2 FISH Probe
The SH3BP2 FISH probe is designed to hybridize to the SH3BP2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SH3BP2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SH3BP2-20-RE | 20 (40 μL) | 200 μL |  |
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| SH3BP2-20-GO | 20 (40 μL) | 200 μL |  |
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| SH3BP2-20-GR | 20 (40 μL) | 200 μL |  |
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| SH3BP2-20-AQ | 20 (40 μL) | 200 μL |  |
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| SH3BP2-20-DIG | 20 (40 μL) | 200 μL |  |
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| SH3BP2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Gene Details
Gene Symbol: SH3BP2
Gene Name: SH3 Domain Binding Protein 2
Chromosome: CHR4: 2794749-2842823
Locus: 4p16.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SH3BP2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SH3BP2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping