SF1 FISH Probe
The SF1 FISH probe is designed to hybridize to the SF1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SF1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SF1-20-RE | 20 (40 μL) | 200 μL |  |
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| SF1-20-GO | 20 (40 μL) | 200 μL |  |
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| SF1-20-GR | 20 (40 μL) | 200 μL |  |
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| SF1-20-AQ | 20 (40 μL) | 200 μL |  |
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| SF1-20-DIG | 20 (40 μL) | 200 μL |  |
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| SF1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Gene Details
Gene Symbol: SF1
Gene Name: Splicing Factor 1
Chromosome: CHR11: 64532075-64546316
Locus: 11q13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SF1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SF1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping