RTN3 FISH Probe
The RTN3 FISH probe is designed to hybridize to the RTN3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RTN3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RTN3-20-RE | 20 (40 μL) | 200 μL |  |
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| RTN3-20-GO | 20 (40 μL) | 200 μL |  |
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| RTN3-20-GR | 20 (40 μL) | 200 μL |  |
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| RTN3-20-AQ | 20 (40 μL) | 200 μL |  |
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| RTN3-20-DIG | 20 (40 μL) | 200 μL |  |
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| RTN3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. [provided by RefSeq, May 2012]
Gene Details
Gene Symbol: RTN3
Gene Name: Reticulon 3
Chromosome: CHR11: 63448921-63527363
Locus: 11q13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RTN3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RTN3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping