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ROS1 FISH Probe

The ROS1 FISH probe is designed to hybridize to the ROS1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
ROS1-20-OR  (Standard Design) 20 (40 μL) 200 μL
ROS1-20-RE 20 (40 μL) 200 μL
ROS1-20-GO 20 (40 μL) 200 μL
ROS1-20-GR 20 (40 μL) 200 μL
ROS1-20-AQ 20 (40 μL) 200 μL
ROS1-20-DIG 20 (40 μL) 200 μL
ROS1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: ROS1

Gene Name: ROS Proto-oncogene 1, Receptor Tyrosine Kinase

Chromosome: CHR6: 117609529-117747018

Locus: 6q22.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Comprehensive Genomic Profiling of Malignant Effusions in Patients with Metastatic Lung Adenocarcinoma

In this study, the utility of performing targeted next-generation sequencing (NGS) on malignant effusions from patients with metastatic lung adenocarcinoma was investigated. NGS is a high throughput technology, which utilizes a small sample input, but the suitability of NGS analysis for tissue-free cytology samples such as malignant body fluids is not well understood. In order to investigate the adequacy of NGS on liquid biopsies of MLA, targeted NGS was performed using custom target panels consisting of many oncogenes. Additional non-NGS molecular tests were performed on the effusion samples, including fluorescence in situ hybridization (FISH) analysis for the oncogene ROS1, using a break-apart FISH probe manufactured by Empire Genomics.
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Product Details

Product: ROS1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ROS1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping