RNY1 FISH Probe
The RNY1 FISH probe is designed to hybridize to the RNY1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
RNY1-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
RNY1-20-RE | 20 (40 μL) | 200 μL | ||
RNY1-20-GO | 20 (40 μL) | 200 μL | ||
RNY1-20-GR | 20 (40 μL) | 200 μL | ||
RNY1-20-AQ | 20 (40 μL) | 200 μL | ||
RNY1-20-DIG | 20 (40 μL) | 200 μL | ||
RNY1-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
Y RNAs are small noncoding RNAs that were originally identified as the RNA component of soluble ribonucleoproteins (RNPs) termed Ro RNPs. Ro RNPs are detected by autoimmune sera of patients suffering from rheumatic diseases, such as from systemic lupus erythematosus (MIM 152700) and Sjogren syndrome (MIM 270200). Ro RNPs consist of a Y RNA that is associated with the autoimmune antigen proteins Ro60 (TROVE2; MIM 600063) and La (SSB; MIM 109090), as well as other proteins. Four human Y RNAs have been identified: Y1, Y3 (RNY3; MIM 601822), Y4 (RNY4; MIM 601823), and Y5 (RNY5; MIM 601824). (Y2 is a truncated form of Y1.) Y RNAs are transcribed by RNA polymerase III and range in size from 83 to 112 nucleotides. They appear to have a functional role in chromosomal DNA replication (Christov et al., 2006 [PubMed 16943439]).[supplied by OMIM, Apr 2009]
Gene Details
Gene Symbol: RNY1
Gene Name: RNA, Ro-associated Y1
Chromosome: CHR7: 148987247-148987135
Locus: 7q36.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RNY1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RNY1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping