RNF139 FISH Probe
The RNF139 FISH probe is designed to hybridize to the RNF139 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RNF139-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RNF139-20-RE | 20 (40 μL) | 200 μL |  |
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| RNF139-20-GO | 20 (40 μL) | 200 μL |  |
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| RNF139-20-GR | 20 (40 μL) | 200 μL |  |
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| RNF139-20-AQ | 20 (40 μL) | 200 μL |  |
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| RNF139-20-DIG | 20 (40 μL) | 200 μL |  |
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| RNF139-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RNF139
Gene Name: Ring Finger Protein 139
Chromosome: CHR8: 125487007-125500859
Locus: 8q24.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RNF139 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RNF139-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping