RET+3 FISH Probe
The RET+3 FISH probe is designed to hybridize to the RET+3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MCS+9.7-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MCS+9.7-20-RE | 20 (40 μL) | 200 μL |  |
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| MCS+9.7-20-GO | 20 (40 μL) | 200 μL |  |
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| MCS+9.7-20-GR | 20 (40 μL) | 200 μL |  |
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| MCS+9.7-20-AQ | 20 (40 μL) | 200 μL |  |
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| MCS+9.7-20-DIG | 20 (40 μL) | 200 μL |  |
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| MCS+9.7-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This region represents a conserved sequence in the first intron of the ret proto-oncogene (RET). This sequence is bound by SRY box 10, homeobox B5, and the NXF-ARNT2 heterodimer and functions as a transcriptional enhancer in the excretory system and central and peripheral nervous systems. Common polymorphisms in this sequence (rs2435357 and rs2506004) can affect binding of transcription factors and may result in decreased expression of RET. Polymorphic alleles are associated with increased risk of Hirschsprung disease (HSCR), and may have a complex affect depending on sex and genetic or structural variation at other loci. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: MCS+9.7
Gene Name: RET Intron 1 Enhancer
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RET+3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MCS+9.7-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping