REN FISH Probe
The REN FISH probe is designed to hybridize to the REN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| REN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| REN-20-RE | 20 (40 μL) | 200 μL |  |
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| REN-20-GO | 20 (40 μL) | 200 μL |  |
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| REN-20-GR | 20 (40 μL) | 200 μL |  |
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| REN-20-AQ | 20 (40 μL) | 200 μL |  |
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| REN-20-DIG | 20 (40 μL) | 200 μL |  |
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| REN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: REN
Gene Name: Renin
Chromosome: CHR1: 204123943-204135465
Locus: 1q32.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: REN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: REN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping