RBM8A FISH Probe
The RBM8A FISH probe is designed to hybridize to the RBM8A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RBM8A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| RBM8A-20-RE | 20 (40 μL) | 200 μL |  |
|
| RBM8A-20-GO | 20 (40 μL) | 200 μL |  |
|
| RBM8A-20-GR | 20 (40 μL) | 200 μL |  |
|
| RBM8A-20-AQ | 20 (40 μL) | 200 μL |  |
|
| RBM8A-20-DIG | 20 (40 μL) | 200 μL |  |
|
| RBM8A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]
Gene Details
Gene Symbol: RBM8A
Gene Name: RNA Binding Motif Protein 8A
Chromosome: CHR1: 145507556-145513535
Locus: 1q21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: RBM8A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RBM8A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping