RAD18 FISH Probe
The RAD18 FISH probe is designed to hybridize to the RAD18 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
RAD18-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
RAD18-20-RE | 20 (40 μL) | 200 μL | ||
RAD18-20-GO | 20 (40 μL) | 200 μL | ||
RAD18-20-GR | 20 (40 μL) | 200 μL | ||
RAD18-20-AQ | 20 (40 μL) | 200 μL | ||
RAD18-20-DIG | 20 (40 μL) | 200 μL | ||
RAD18-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RAD18
Gene Name: RAD18, E3 Ubiquitin Protein Ligase
Chromosome: CHR3: 8918879-9005159
Locus: 3p25.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RAD18 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RAD18-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping