PTPN2 FISH Probe
The PTPN2 FISH probe is designed to hybridize to the PTPN2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTPN2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PTPN2-20-RE | 20 (40 μL) | 200 μL |  |
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| PTPN2-20-GO | 20 (40 μL) | 200 μL |  |
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| PTPN2-20-GR | 20 (40 μL) | 200 μL |  |
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| PTPN2-20-AQ | 20 (40 μL) | 200 μL |  |
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| PTPN2-20-DIG | 20 (40 μL) | 200 μL |  |
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| PTPN2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011]
Gene Details
Gene Symbol: PTPN2
Gene Name: Protein Tyrosine Phosphatase, Non-receptor Type 2
Chromosome: CHR18: 12785476-12884334
Locus: 18p11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PTPN2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PTPN2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping