PRSS2 FISH Probe
The PRSS2 FISH probe is designed to hybridize to the PRSS2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRSS2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PRSS2-20-RE | 20 (40 μL) | 200 μL |  |
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| PRSS2-20-GO | 20 (40 μL) | 200 μL |  |
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| PRSS2-20-GR | 20 (40 μL) | 200 μL |  |
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| PRSS2-20-AQ | 20 (40 μL) | 200 μL |  |
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| PRSS2-20-DIG | 20 (40 μL) | 200 μL |  |
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| PRSS2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2015]
Gene Details
Gene Symbol: PRSS2
Gene Name: Protease, Serine 2
Chromosome: CHR7: 142479907-142481378
Locus: 7q34
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PRSS2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRSS2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping