PRKCH FISH Probe
The PRKCH FISH probe is designed to hybridize to the PRKCH gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRKCH-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PRKCH-20-RE | 20 (40 μL) | 200 μL |  |
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| PRKCH-20-GO | 20 (40 μL) | 200 μL |  |
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| PRKCH-20-GR | 20 (40 μL) | 200 μL |  |
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| PRKCH-20-AQ | 20 (40 μL) | 200 μL |  |
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| PRKCH-20-DIG | 20 (40 μL) | 200 μL |  |
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| PRKCH-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. Mutations in this gene are associated with susceptibility to cerebral infarction. [provided by RefSeq, Sep 2015]
Gene Details
Gene Symbol: PRKCH
Gene Name: Protein Kinase C Eta
Chromosome: CHR14: 61788514-62017698
Locus: 14q23.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PRKCH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRKCH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping