PRKAB1 FISH Probe
The PRKAB1 FISH probe is designed to hybridize to the PRKAB1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRKAB1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PRKAB1-20-RE | 20 (40 μL) | 200 μL |  |
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| PRKAB1-20-GO | 20 (40 μL) | 200 μL |  |
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| PRKAB1-20-GR | 20 (40 μL) | 200 μL |  |
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| PRKAB1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PRKAB1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PRKAB1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PRKAB1
Gene Name: Protein Kinase AMP-activated Non-catalytic Subunit Beta 1
Chromosome: CHR12: 120105760-120119429
Locus: 12q24.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PRKAB1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRKAB1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping