PRF1 FISH Probe
The PRF1 FISH probe is designed to hybridize to the PRF1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRF1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PRF1-20-RE | 20 (40 μL) | 200 μL |  |
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| PRF1-20-GO | 20 (40 μL) | 200 μL |  |
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| PRF1-20-GR | 20 (40 μL) | 200 μL |  |
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| PRF1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PRF1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PRF1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: PRF1
Gene Name: Perforin 1
Chromosome: CHR10: 72357103-72362531
Locus: 10q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PRF1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRF1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping