PRELP FISH Probe
The PRELP FISH probe is designed to hybridize to the PRELP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PRELP-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
PRELP-20-RE | 20 (40 μL) | 200 μL | ||
PRELP-20-GO | 20 (40 μL) | 200 μL | ||
PRELP-20-GR | 20 (40 μL) | 200 μL | ||
PRELP-20-AQ | 20 (40 μL) | 200 μL | ||
PRELP-20-DIG | 20 (40 μL) | 200 μL | ||
PRELP-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PRELP
Gene Name: Proline And Arginine Rich End Leucine Rich Repeat Protein
Chromosome: CHR1: 203444882-203460479
Locus: 1q32.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PRELP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRELP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping