PNPO FISH Probe
The PNPO FISH probe is designed to hybridize to the PNPO gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PNPO-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PNPO-20-RE | 20 (40 μL) | 200 μL |  |
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| PNPO-20-GO | 20 (40 μL) | 200 μL |  |
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| PNPO-20-GR | 20 (40 μL) | 200 μL |  |
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| PNPO-20-AQ | 20 (40 μL) | 200 μL |  |
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| PNPO-20-DIG | 20 (40 μL) | 200 μL |  |
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| PNPO-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq, Oct 2008]
Gene Details
Gene Symbol: PNPO
Gene Name: Pyridoxamine 5'-phosphate Oxidase
Chromosome: CHR17: 46018888-46026674
Locus: 17q21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PNPO FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PNPO-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping