PN5 FISH Probe
The PN5 FISH probe is designed to hybridize to the PN5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SCN11A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| SCN11A-20-RE | 20 (40 μL) | 200 μL |  |
|
| SCN11A-20-GO | 20 (40 μL) | 200 μL |  |
|
| SCN11A-20-GR | 20 (40 μL) | 200 μL |  |
|
| SCN11A-20-AQ | 20 (40 μL) | 200 μL |  |
|
| SCN11A-20-DIG | 20 (40 μL) | 200 μL |  |
|
| SCN11A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is highly expressed in nociceptive neurons of dorsal root ganglia and trigeminal ganglia. It mediates brain-derived neurotrophic factor-evoked membrane depolarization and is a major effector of peripheral inflammatory pain hypersensitivity. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy type VII and familial episodic pain syndrome-3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2017]
Gene Details
Gene Symbol: SCN11A
Gene Name: Sodium Voltage-gated Channel Alpha Subunit 11
Chromosome: CHR3: 38887259-38992052
Locus: 3p22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: PN5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SCN11A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping