PFM5 FISH Probe
The PFM5 FISH probe is designed to hybridize to the PFM5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRDM8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PRDM8-20-RE | 20 (40 μL) | 200 μL |  |
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| PRDM8-20-GO | 20 (40 μL) | 200 μL |  |
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| PRDM8-20-GR | 20 (40 μL) | 200 μL |  |
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| PRDM8-20-AQ | 20 (40 μL) | 200 μL |  |
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| PRDM8-20-DIG | 20 (40 μL) | 200 μL |  |
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| PRDM8-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein that belongs to a conserved family of histone methyltransferases that predominantly act as negative regulators of transcription. The encoded protein contains an N-terminal Su(var)3-9, Enhancer-of-zeste, and Trithorax (SET) domain and a double zinc-finger domain. Knockout of this gene in mouse results in mistargeting by neurons of the dorsal telencephalon, abnormal itch-like behavior, and impaired differentiation of rod bipolar cells. In humans, the protein has been shown to interact with the phosphatase laforin and the ubiquitin ligase malin, which regulate glycogen construction in the cytoplasm. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Details
Gene Symbol: PRDM8
Gene Name: PR/SET Domain 8
Chromosome: CHR4: 81106423-81125482
Locus: 4q21.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PFM5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRDM8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping