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PDCD1 FISH Probe

The PDCD1 FISH probe is designed to hybridize to the PDCD1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

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Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
PDCD1-20-OR  (Standard Design) 20 (40 μL) 200 μL
PDCD1-20-RE 20 (40 μL) 200 μL
PDCD1-20-GO 20 (40 μL) 200 μL
PDCD1-20-GR 20 (40 μL) 200 μL
PDCD1-20-AQ 20 (40 μL) 200 μL
PDCD1-20-DIG 20 (40 μL) 200 μL
PDCD1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: PDCD1

Gene Name: Programmed Cell Death 1

Chromosome: CHR2: 242792032-242801058

Locus: 2q37.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

High-throughput Sequencing of Subcutaneous Panniculitis-like T-Cell Lymphoma Reveals Candidate Pathogenic Mutations

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare cancer that’s challenging to distinguish from lupus panniculitis (LP). Few studies have been conducted on the genetic and molecular development of the disease. This team performed whole-exome sequencing on 4 SPTCLs and 1 systemic T-cell lymphoma, along with 2 cases of LP. They also used targeted sequencing to analyze 41 genes (with known implications across hematolyhpoid malignancies) on 5 additional SPTCL biopsies. Empire Genomics’ PDCD1 and PIK3CD FISH probes were used to detect copy number variants in the 2 genes, which are abnormalities associated with lymphoma but not LP.
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Product Details

Product: PDCD1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PDCD1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping