OPN4 FISH Probe
The OPN4 FISH probe is designed to hybridize to the OPN4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
OPN4-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
OPN4-20-RE | 20 (40 μL) | 200 μL | ||
OPN4-20-GO | 20 (40 μL) | 200 μL | ||
OPN4-20-GR | 20 (40 μL) | 200 μL | ||
OPN4-20-AQ | 20 (40 μL) | 200 μL | ||
OPN4-20-DIG | 20 (40 μL) | 200 μL | ||
OPN4-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: OPN4
Gene Name: Opsin 4
Chromosome: CHR10: 88414313-88426216
Locus: 10q23.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: OPN4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: OPN4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping